Do you use Twitter to stay in touch with your friends / colleagues / clients and just randomness of the world? If you don’t you should be because it increases the inflow of the world’s news into your life and makes it easier to stay intouch with everything. For the longest time I’ve been a very avid user of Tweetdeck, but the only complaint I’ve had with Tweetdeck is that it did not support multiple accounts. I have found my desktop solution to that with Seesmic Desktop.